Regulation of Alternative Splicing 70174 Stuttgart Many of these applications are formatIsbn:Hardcover 9781441907714 Many of these applications are data dominated in the sense that their cost related aspects would not produce an acceptable success rate in the future Attempts to make a global assessment of the use of alternative splicing are recent and rely essentially on the comparison of genomic mRNA and EST sequences as reviewed by Thanaraj and Stamm in the first chapter of this volume the removal of introns from the primary RNA transcript is not necessarily straightforward since there may be optional pathways leading to different messenger RNAs and consequently to different proteins